This paper illustrates the potential for 3D OCT algorithms to improve in vivo imaging in glaucoma.Īrtifact glaucoma minimum distance band optic nerve optical coherence tomography.Ĭhen TC.
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For clinically significant artifact rates per eye, optic nerve scans had significantly fewer artifacts (15.8% of glaucomatous eyes, 13.2% of normal eyes) compared to RNFL scans (61.7% of glaucomatous eyes, 25.4% of normal eyes) (glaucoma group: 95% CI, 34.1-57.5, P < 0.0001 normal group: 95% CI, 1.3-23.3, P = 0.03).Ĭompared to the most commonly used RNFL thickness scans, optic nerve volume scans less frequently require manual correction or repeat scanning to obtain accurate measurements. A clinically significant artifact was defined as one requiring manual correction or repeat scanning.Īmong glaucomatous eyes, artifact rates per B-scan were significantly more common in RNFL scans (61.7%, 74 of 120) compared to B-scans in neuroretinal rim volume scans (20.9%, 1423 of 6820) (95% confidence interval, 31.6-50.0 P < 0.0001). Global MDB neuroretinal rim thicknesses were calculated before and after manual deletion of B-scans with artifacts and subsequent automated interpolation. Neuroretinal rim tissue was quantified by the minimum distance band (MDB). For RNFL scans and optic nerve scans, 15 artifact types were calculated per B-scan and per eye. Only one eye per patient was used for analysis of 120 glaucoma patients and 114 normal patients. To compare the rates of clinically significant artifacts for two-dimensional peripapillary retinal nerve fiber layer (RNFL) thickness versus three-dimensional (3D) neuroretinal rim thickness using spectral-domain optical coherence tomography (SD-OCT).